What Is Semaglutide?
Semaglutide is an FDA-approved medication originally developed for type 2 diabetes that has shown remarkable results for weight loss. It belongs to a class of drugs called GLP-1 receptor agonists, which mimic a naturally occurring hormone in your body.
How GLP-1 Controls Your Appetite
When you eat, your intestines release a hormone called glucagon-like peptide-1 (GLP-1). This hormone signals your brain that you're full, slows down how quickly food leaves your stomach, and helps regulate blood sugar levels.
Semaglutide works by mimicking this hormone at much higher levels than your body naturally produces, creating a stronger and longer-lasting feeling of fullness after meals.
What Does the Research Say?
Clinical trials have shown impressive results:
- STEP 1 Trial: Participants lost an average of 14.9% of their body weight over 68 weeks
- STEP 3 Trial: Combined with intensive behavioral therapy, average weight loss reached 16%
- Most participants saw significant improvements in blood pressure, cholesterol, and blood sugar
What to Expect During Treatment
Treatment typically begins with a low dose that gradually increases over several weeks. This approach helps minimize side effects while your body adjusts. Most patients begin noticing reduced appetite within the first 2-4 weeks.
Is Semaglutide Right for You?
Semaglutide is generally recommended for adults with a BMI of 30 or higher, or 27+ with at least one weight-related condition. The best way to determine if it's right for you is through a consultation with our medical team at Monaco Health.
Ready to learn more? Schedule a free consultation to discuss whether GLP-1 therapy is the right path for your weight loss goals.
